The scandal-hit Mid Staffordshire NHS Trust faces being dissolved after regulators announced the administration process was to begin.
The trust has been at the centre of one of the worst health scandals in history after neglect and abuse led to hundreds of needless deaths from 2005 to 2008.
Mid Staffordshire has also faced serious financial problems and has had to be bailed out by government.
Monitor has now decided it should be put into administration.
This means an independent administrator will take over the running of the trust before coming up with proposals for the long-term.
A range of options are available, including closing down the trust altogether. If this happens essential services would be taken on by another organisation.
The administrator could also recommend the trust not be scrapped although it would not exist in its current form.
Monitor has decided "in principle" the process should start, although other bodies need to be consulted before the process officially starts.
That is only expected to take a couple of weeks.
Not sustainableIt is the second time an NHS trust has faced such a process - earlier this year the decision to break up South London Healthcare was agreed.
Mid Staffordshire looks after Stafford and Cannock Chase Hospitals.
A report by Monitor earlier this year highlighted financial problems at the trust - in order to break even there would need to be savings of 7% of its yearly budget.
It said the trust was neither clinically nor financially sustainable in its current form in the long term.
Care at the hospital was so poor that patients were left in soiled sheets while others were so dehydrated they drank from flower vases.
A Freedom of Information request by the BBC showed that falling public confidence in Stafford Hospital was costing the trust nearly £4m a year.
It showed there had been a 67% drop in the number of patients in the past five years as they were choosing to "have their treatment elsewhere".
David Bennett, the chief executive of Monitor, said: "We are now consulting on whether to appoint Trust Special Administrators with the expertise to reorganise services in a way which is clinically robust and sustainable.
"Their priority will be to make sure that patients can continue to access the services that they need and they will work with the local community to do this.
"Taking into account the consultation process, it would be several weeks before Trust Special Administrators were in place."
The process of administration would need to include a plan for reorganising health services in the area and would need to be approved by the Secretary of State.
The Department of Health in England said the trust was "still facing serious financial challenges".
A spokesperson said: "This puts at risk its work on improving services for patients. It is important that valued local services will last and are able to continue providing high quality treatment and advice for patients.
"We appreciate that this is an area where people are going to hold strong views.
"Monitor will now consult with key stakeholders, including the Secretary of State for Health, before making a final decision on the appointment."
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